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life
shēng huó
生活
·HSK 4

scientist / researcher
kēxuéjiā
科学家
to discover / to find
fāxiàn
发现
schizophrenia
jīngshén fēnlièzhèng
精神分裂症
key / crucial
guānjiàn
关键
gene
jīyīn
基因
mutation
tūbiàn
突变
mechanism
jīzhì
机制
。

MIT (Massachusetts Institute of Technology)
Máshěng Lǐgōng Xuéyuàn
麻省理工学院
and / with
yǔ
与
Broad Institute
Bódé Yánjiūsuǒ
博德研究所
(attributive particle)
de
的
scientist / researcher
kēxuéjiā
科学家
to discover / to find
fāxiàn
发现
，
grin2a (gene name)
grin2a
grin2a
gene
jīyīn
基因
mutation
tūbiàn
突变
will / would
huì
会
to damage / to impair
sǔnhài
损害
brain
dànǎo
大脑
thalamus
qiūnǎo
丘脑
and / with
yǔ
与
prefrontal cortex
qián é yè pícéng
前额叶皮层
between
jiān
间
(attributive particle)
de
的
key / critical
guānjiàn
关键
neural pathway
shénjīng tōnglù
神经通路
，
to cause / to make
shǐ
使
patient / sufferer
huànzhě
患者
difficult to / hard to
nányǐ
难以
based on / according to
gēnjù
根据
new information
xīn xìnxī
新信息
to update / to renew
gēngxīn
更新
cognition / perception
rènzhī
认知
。
researcher / research team
yánjiū rényuán
研究人员
through / by means of
tōngguò
通过
animal experiment
dòngwù shíyàn
动物实验
to verify / to confirm
yànzhèng
验证
(completion particle)
le
了
this
zhè yī
这一
mechanism
jīzhì
机制
，
and / moreover
bìng
并
to state / to indicate
biǎoshì
表示
this discovery
cǐ fāxiàn
此发现
for / provides
wèi
为
to develop
kāifā
开发
schizophrenia
jīngshén fēnlièzhèng
精神分裂症
new therapy / new treatment
xīn liáofǎ
新疗法
to provide / to offer
tígōng
提供
(completion particle)
le
了
important
zhòngyào
重要
target / drug target
bǎdiǎn
靶点
。

April 3, 2026 at 2:00 PM

April 2nd (the date)
sì yuè èr rì
四月二日
，
Nature Neuroscience (journal)
Zìrán Shénjīng Kēxué
《自然神经科学》
journal / magazine
zázhì
杂志
to publish / to release
fābiǎo
发表
(completion particle)
le
了
one / a
yī xiàng
一项
about / regarding
guānyú
关于
schizophrenia
jīngshén fēnlièzhèng
精神分裂症
genetic mechanism
yíchuán jīzhì
遗传机制
(attributive particle)
de
的
important
zhòngyào
重要
research / study
yánjiū
研究
。
from / coming from
láizì
来自
MIT (Massachusetts Institute of Technology)
Máshěng Lǐgōng Xuéyuàn
麻省理工学院
and
hé
和
Broad Institute
Bódé Yánjiūsuǒ
博德研究所
(attributive particle)
de
的
researcher / research team
yánjiū rényuán
研究人员
to discover / to find
fāxiàn
发现
，
grin2a (gene name)
grin2a
grin2a
gene
jīyīn
基因
mutation
tūbiàn
突变
is / to be
shì
是
to trigger / to cause
yǐnfā
引发
some / partial
bùfen
部分
schizophrenia
jīngshén fēnlièzhèng
精神分裂症
symptom
zhèngzhuàng
症状
(attributive particle)
de
的
key / crucial
guānjiàn
关键
reason / cause
yuányīn
原因
one of
zhī yī
之一
。
grin2a (gene name)
grin2a
grin2a
gene
jīyīn
基因
responsible for / in charge of
fùzé
负责
to encode / to code for
biānmǎ
编码
NMDA (receptor type)
NMDA
NMDA
receptor
shòutǐ
受体
(attributive particle)
de
的
important
zhòngyào
重要
component / constituent part
zǔchéng bùfen
组成部分
，
this / the said
gāi
该
receptor
shòutǐ
受体
in / at
zài
在
neuron
shénjīng yuán
神经元
signal
xìnhào
信号
transmission / to transmit
chuándì
传递
in / among
zhōng
中
to play (a role) / to bring into play
fāhuī
发挥
core / central
héxīn
核心
role / function
zuòyòng
作用
。
researcher / research team
yánjiū rényuán
研究人员
through / by means of
tōngguò
通过
experiment
shíyàn
实验
to confirm / to verify
quèrèn
确认
，
this type of / this kind of
zhèzhǒng
这种
mutation
tūbiàn
突变
will / would
huì
会
to damage / to impair
sǔnhài
损害
thalamus
qiūnǎo
丘脑
and / with
yǔ
与
prefrontal cortex
qián é yè pícéng
前额叶皮层
between
zhījiān
之间
(attributive particle)
de
的
neural connection
shénjīng liánjié
神经连接
。
normal / regular
zhèngcháng
正常
under normal circumstances
qíngkuàng xià
情况下
，
this (path/route)
zhètiáo
这条
neural pathway
shénjīng tōnglù
神经通路
to help
bāngzhù
帮助
brain
dànǎo
大脑
based on / according to
gēnjù
根据
new information
xīn xìnxī
新信息
continuously / constantly
bùduàn
不断
to correct / to revise
xiūzhèng
修正
toward / about
duì
对
reality
xiànshí
现实
(attributive particle)
de
的
understanding / comprehension
lǐjiě
理解
。
once / if
yīdàn
一旦
this (path/route)
zhètiáo
这条
pathway / channel
tōnglù
通路
damaged / impaired
shòusǔn
受损
，
patient / sufferer
huànzhě
患者
then / consequently
biàn
便
difficult to / hard to
nányǐ
难以
to use / using
yòng
用
new information
xīn xìnxī
新信息
to update / to renew
gēngxīn
更新
cognition / perception
rènzhī
认知
，
and thereby / furthermore
jìn ér
进而
possibly / may
kěnéng
可能
to appear / to develop
chūxiàn
出现
with
yǔ
与
reality
xiànshí
现实
to become detached from / disconnected
tuōjié
脱节
(attributive particle)
de
的
symptom
zhèngzhuàng
症状
。
in / during
zài
在
animal experiment
dòngwù shíyàn
动物实验
in / within
zhōng
中
，
researcher / research team
yánjiū rényuán
研究人员
through / by means of
tōngguò
通过
artificial / manual
réngōng
人工
to activate / to stimulate
jīhuó
激活
this (path/route)
zhètiáo
这条
pathway
tōnglù
通路
，
successfully
chénggōng
成功
to restore / to recover
huīfù
恢复
(completion particle)
le
了
animal
dòngwù
动物
(attributive particle)
de
的
normal
zhèngcháng
正常
behavior
xíngwéi
行为
。
this
zhè yī
这一
achievement / finding
chéngguǒ
成果
for / provides
wèi
为
to develop
kāifā
开发
specifically / specially
zhuānmén
专门
aimed at / targeting
zhēnduì
针对
this
cǐ
此
neural circuit
shénjīng huílù
神经回路
(attributive particle)
de
的
new type / novel
xīnxíng
新型
antipsychotic
kàng jīngshénbìng
抗精神病
drug / medication
yàowù
药物
to provide / to offer
tígōng
提供
(completion particle)
le
了
important
zhòngyào
重要
direction / target
fāngxiàng
方向
。
scientist / researcher
kēxuéjiā
科学家
to state / to indicate
biǎoshì
表示
，
the next step
xià yī bù
下一步
will
jiāng
将
to advance / to push forward
tuījìn
推进
human body / human
réntǐ
人体
clinical trial
línchuáng shìyàn
临床试验
，
in order to / so as to
yǐ
以
to verify / to confirm
yànzhèng
验证
related / relevant
xiāngguān
相关
therapy / treatment
liáofǎ
疗法
(attributive particle)
de
的
safety
ānquánxìng
安全性
and
hé
和
effectiveness / efficacy
yǒuxiàoxìng
有效性
。

News in English

Lifestyle & Culture

MIT Scientists Find Gene Mutation That Traps Brain in Wrong Reality, Offering Clue to Schizophrenia

Researchers from MIT and the Broad Institute found that a mutation in the grin2a gene disrupts a key thalamus-prefrontal cortex circuit, preventing the brain from updating beliefs, and restored normal behavior in mice by reactivating the pathway.

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final / championship match
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to face / to compete against
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dì sān lún
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jiāng
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to face / to take on (in competition)
yíngzhàn
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lìshǐ jìlù
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