studyyánjiū研究：to stop usingtíngyòng停用GLP-1 (weight-loss drug class)GLP-1GLP-1weight-loss drugsjiǎnféiyào减肥药afterhòu后body weighttǐzhòng体重to rebound / regainfǎntán反弹rate / speedsùdù速度compared tobǐ比dietingjiéshí节食fasterkuài快four timessì bèi四倍。
study
yánjiū
研究
to stop using
tíngyòng
停用
GLP-1 (weight-loss drug class)
GLP-1
GLP-1
weight-loss drugs
jiǎnféiyào
减肥药
after
hòu
后
body weight
tǐzhòng
体重
to rebound / regain
fǎntán
反弹
rate / speed
sùdù
速度
compared to
bǐ
比
dieting
jiéshí
节食
faster
kuài
快
four times
sì bèi
四倍
multiple
duō xiàng
多项
January 2026
2026 nián 1 yuè
2026年1月
published
fābiǎo
发表
(structural particle)
de
的
studies
yánjiū
研究
found
fāxiàn
发现
to stop using
tíngyòng
停用
Ozempic (weight-loss drug)
Ozempic
Ozempic
and similar
děng
等
GLP-1 (drug class)
GLP-1
GLP-1
class / type
lèi
类
weight-loss drugs
jiǎnféiyào
减肥药
after
hòu
后
patients
huànzhě
患者
body weight
tǐzhòng
体重
often / tend to
wǎngwǎng
往往
rapidly
xùnsù
迅速
rebound
fǎntán
反弹
compared to
yǔ
与
relying only on
jǐn kào
仅靠
diet
yǐnshí
饮食
and
hé
和
exercise
yùndòng
运动
weight loss
jiǎnféi
减肥
(structural particle)
de
的
people
rén
人
compared to
xiāngbǐ
相比
stopping medication
tíngyào
停药
patients
huànzhě
患者
(structural particle)
de
的
body weight
tǐzhòng
体重
rebound
fǎntán
反弹
rate
sùdù
速度
approximately
yuē
约
faster
kuài
快
four times
sì bèi
四倍
January 10, 2026 at 2:00 PM
multiple
duō xiàng
多项
published
fābiǎo
发表
in
yú
于
January 2026
2026 nián 1 yuè
2026年1月
(structural particle)
de
的
medical
yīxué
医学
studies
yánjiū
研究
show / indicate
xiǎnshì
显示
to stop using
tíngyòng
停用
GLP-1 (drug class)
GLP-1
GLP-1
class / type
lèi
类
weight-loss drugs
jiǎnféiyào
减肥药
after
hòu
后
patients
huànzhě
患者
body weight
tǐzhòng
体重
often / tend to
wǎngwǎng
往往
rapidly
xùnsù
迅速
rebound
fǎntán
反弹
research
yánjiū
研究
data
shùjù
数据
indicate / show
biǎomíng
表明
to take (medicine)
fúyòng
服用
Ozempic (weight-loss drug)
Ozempic
Ozempic
and similar
děng
等
drugs
yàowù
药物
(structural particle)
de
的
patients
huànzhě
患者
average
píngjūn
平均
weight loss
jiǎnzhòng
减重
approximately
yuē
约
15 kilograms / about 33 pounds
15 gōngjīn
15公斤
but
dàn
但
stopping medication
tíngyào
停药
about one year later
yuē yī nián hòu
约一年后
usually
tōngcháng
通常
regain / rebound
fǎntán
反弹
approximately
yuē
约
10 kilograms / about 22 pounds
10 gōngjīn
10公斤
compared to
yǔ
与
relying only on
jǐn kào
仅靠
diet
yǐnshí
饮食
and
hé
和
exercise
yùndòng
运动
weight loss
jiǎnféi
减肥
(structural particle)
de
的
people
rén
人
compared to
xiāngbǐ
相比
stopping medication
tíngyào
停药
after
hòu
后
(structural particle)
de
的
body weight
tǐzhòng
体重
rebound
fǎntán
反弹
rate
sùdù
速度
is approximately
yuē wéi
约为
the latter
hòuzhě
后者
(structural particle)
de
的
four times
sì bèi
四倍
University of Oxford
Niújīn Dàxué
牛津大学
(structural particle)
de
的
research team
yánjiū tuánduì
研究团队
pointed out
zhǐchū
指出
stopping medication
tíngyào
停药
approximately
yuē
约
17 months
17 gè yuè
17个月
after
hòu
后
patients
huànzhě
患者
(structural particle)
de
的
blood pressure
xuèyā
血压
and
hé
和
cholesterol
dǎngùchún
胆固醇
levels
shuǐpíng
水平
also
yě
也
will
huì
会
return to
huīfù dào
恢复到
before taking the medication
yòngyào qián
用药前
(structural particle)
de
的
state / condition
zhuàngtài
状态
however
rán ér
然而
United States
Měiguó
美国
Cleveland Clinic
Kèlìfūlán Zhěnsuǒ
克利夫兰诊所
a
yī xiàng
一项
covering
hángài
涵盖
nearly
jìn
近
8,000
bā qiān míng
八千名
patients
huànzhě
患者
(structural particle)
de
的
real-world study
zhēnshí shìjiè yánjiū
真实世界研究
shows
xiǎnshì
显示
many people
xǔduō rén
许多人
stopping medication
tíngyào
停药
after
hòu
后
will
huì
会
again
chóngxīn
重新
use medication
yòngyào
用药
actual
shíjì
实际
rebound
fǎntán
反弹
situation
qíngkuàng
情况
may
kěnéng
可能
relatively
xiāngduì
相对
mild / moderate
wēnhé
温和
multiple
duō wèi
多位
experts
zhuānjiā
专家
stated
biǎoshì
表示
GLP-1 (drug class)
GLP-1
GLP-1
class / type
lèi
类
drugs
yàowù
药物
better / more
gèng
更
suitable
shìhé
适合
to serve as
zuòwéi
作为
long-term
cháng qī
长期
maintenance
wéichí
维持
treatment
zhìliáo
治疗
approach / means
shǒuduàn
手段
rather than
ér fēi
而非
short-term
duǎn qī
短期
intervention
gānyù
干预
measures
cuòshī
措施
currently
mùqián
目前
Ozempic (weight-loss drug)
Ozempic
Ozempic
and similar
děng
等
drugs
yàowù
药物
(structural particle)
de
的
annual cost
nián fèiyòng
年费用
as high as
gāodá
高达
thousands of dollars
shù qiān měiyuán
数千美元
long-term
cháng qī
长期
use
shǐyòng
使用
for
duì
对
many
xǔduō
许多
patients
huànzhě
患者
in terms of
ér yán
而言
financial
jīngjì
经济
burden
fùdān
负担
relatively heavy
jiào zhòng
较重
doctors
yīshēng
医生
recommend
jiànyì
建议
patients
huànzhě
患者
before
zài
在
stopping medication
tíngyào
停药
before
qián
前
with
yǔ
与
medical team
yīliáo tuánduì
医疗团队
fully / thoroughly
chōngfèn
充分
communicate
gōutōng
沟通
jointly
gòngtóng
共同
formulate
zhìdìng
制定
personalized
gèxìnghuà
个性化
(structural particle)
de
的
long-term
cháng qī
长期
weight
tǐzhòng
体重
management
guǎnlǐ
管理
plan / program
fāng àn
方案
News in English
Lifestyle & CultureStudy Finds Weight Regain After Stopping GLP-1 Drugs Is Four Times Faster Than Dieting
Multiple studies published in January 2026 found that patients who stop taking GLP-1 drugs such as Ozempic tend to regain weight rapidly. Compared to people who rely only on diet and exercise, those who stop the drugs regain weight about four times faster.
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