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life
shēng huó
生活
·HSK 4

study
yánjiū
研究
to stop using
tíngyòng
停用
GLP-1 (weight-loss drug class)
GLP-1
GLP-1
weight-loss drugs
jiǎnféiyào
减肥药
after
hòu
body weight
tǐzhòng
体重
to rebound / regain
fǎntán
反弹
rate / speed
sùdù
速度
compared to
dieting
jiéshí
节食
faster
kuài
four times
sì bèi
四倍

multiple
duō xiàng
多项
January 2026
2026 nián 1 yuè
2026年1月
published
fābiǎo
发表
(structural particle)
de
studies
yánjiū
研究
found
fāxiàn
发现
to stop using
tíngyòng
停用
Ozempic (weight-loss drug)
Ozempic
Ozempic
and similar
děng
GLP-1 (drug class)
GLP-1
GLP-1
class / type
lèi
weight-loss drugs
jiǎnféiyào
减肥药
after
hòu
patients
huànzhě
患者
body weight
tǐzhòng
体重
often / tend to
wǎngwǎng
往往
rapidly
xùnsù
迅速
rebound
fǎntán
反弹
compared to
relying only on
jǐn kào
仅靠
diet
yǐnshí
饮食
and
exercise
yùndòng
运动
weight loss
jiǎnféi
减肥
(structural particle)
de
people
rén
compared to
xiāngbǐ
相比
stopping medication
tíngyào
停药
patients
huànzhě
患者
(structural particle)
de
body weight
tǐzhòng
体重
rebound
fǎntán
反弹
rate
sùdù
速度
approximately
yuē
faster
kuài
four times
sì bèi
四倍

January 10, 2026 at 2:00 PM

multiple
duō xiàng
多项
published
fābiǎo
发表
in
January 2026
2026 nián 1 yuè
2026年1月
(structural particle)
de
medical
yīxué
医学
studies
yánjiū
研究
show / indicate
xiǎnshì
显示
to stop using
tíngyòng
停用
GLP-1 (drug class)
GLP-1
GLP-1
class / type
lèi
weight-loss drugs
jiǎnféiyào
减肥药
after
hòu
patients
huànzhě
患者
body weight
tǐzhòng
体重
often / tend to
wǎngwǎng
往往
rapidly
xùnsù
迅速
rebound
fǎntán
反弹
research
yánjiū
研究
data
shùjù
数据
indicate / show
biǎomíng
表明
to take (medicine)
fúyòng
服用
Ozempic (weight-loss drug)
Ozempic
Ozempic
and similar
děng
drugs
yàowù
药物
(structural particle)
de
patients
huànzhě
患者
average
píngjūn
平均
weight loss
jiǎnzhòng
减重
approximately
yuē
15 kilograms / about 33 pounds
15 gōngjīn
15公斤
but
dàn
stopping medication
tíngyào
停药
about one year later
yuē yī nián hòu
约一年后
usually
tōngcháng
通常
regain / rebound
fǎntán
反弹
approximately
yuē
10 kilograms / about 22 pounds
10 gōngjīn
10公斤
compared to
relying only on
jǐn kào
仅靠
diet
yǐnshí
饮食
and
exercise
yùndòng
运动
weight loss
jiǎnféi
减肥
(structural particle)
de
people
rén
compared to
xiāngbǐ
相比
stopping medication
tíngyào
停药
after
hòu
(structural particle)
de
body weight
tǐzhòng
体重
rebound
fǎntán
反弹
rate
sùdù
速度
is approximately
yuē wéi
约为
the latter
hòuzhě
后者
(structural particle)
de
four times
sì bèi
四倍
University of Oxford
Niújīn Dàxué
牛津大学
(structural particle)
de
research team
yánjiū tuánduì
研究团队
pointed out
zhǐchū
指出
stopping medication
tíngyào
停药
approximately
yuē
17 months
17 gè yuè
17个月
after
hòu
patients
huànzhě
患者
(structural particle)
de
blood pressure
xuèyā
血压
and
cholesterol
dǎngùchún
胆固醇
levels
shuǐpíng
水平
also
will
huì
return to
huīfù dào
恢复到
before taking the medication
yòngyào qián
用药前
(structural particle)
de
state / condition
zhuàngtài
状态
however
rán ér
然而
United States
Měiguó
美国
Cleveland Clinic
Kèlìfūlán Zhěnsuǒ
克利夫兰诊所
a
yī xiàng
一项
covering
hángài
涵盖
nearly
jìn
8,000
bā qiān míng
八千名
patients
huànzhě
患者
(structural particle)
de
real-world study
zhēnshí shìjiè yánjiū
真实世界研究
shows
xiǎnshì
显示
many people
xǔduō rén
许多人
stopping medication
tíngyào
停药
after
hòu
will
huì
again
chóngxīn
重新
use medication
yòngyào
用药
actual
shíjì
实际
rebound
fǎntán
反弹
situation
qíngkuàng
情况
may
kěnéng
可能
relatively
xiāngduì
相对
mild / moderate
wēnhé
温和
multiple
duō wèi
多位
experts
zhuānjiā
专家
stated
biǎoshì
表示
GLP-1 (drug class)
GLP-1
GLP-1
class / type
lèi
drugs
yàowù
药物
better / more
gèng
suitable
shìhé
适合
to serve as
zuòwéi
作为
long-term
cháng qī
长期
maintenance
wéichí
维持
treatment
zhìliáo
治疗
approach / means
shǒuduàn
手段
rather than
ér fēi
而非
short-term
duǎn qī
短期
intervention
gānyù
干预
measures
cuòshī
措施
currently
mùqián
目前
Ozempic (weight-loss drug)
Ozempic
Ozempic
and similar
děng
drugs
yàowù
药物
(structural particle)
de
annual cost
nián fèiyòng
年费用
as high as
gāodá
高达
thousands of dollars
shù qiān měiyuán
数千美元
long-term
cháng qī
长期
use
shǐyòng
使用
for
duì
many
xǔduō
许多
patients
huànzhě
患者
in terms of
ér yán
而言
financial
jīngjì
经济
burden
fùdān
负担
relatively heavy
jiào zhòng
较重
doctors
yīshēng
医生
recommend
jiànyì
建议
patients
huànzhě
患者
before
zài
stopping medication
tíngyào
停药
before
qián
with
medical team
yīliáo tuánduì
医疗团队
fully / thoroughly
chōngfèn
充分
communicate
gōutōng
沟通
jointly
gòngtóng
共同
formulate
zhìdìng
制定
personalized
gèxìnghuà
个性化
(structural particle)
de
long-term
cháng qī
长期
weight
tǐzhòng
体重
management
guǎnlǐ
管理
plan / program
fāng àn
方案

New Words

jiǎnféiyào
减肥药
weight-loss drug
tǐzhòng
体重
body weight
fǎntán
反弹
to rebound
tíngyào
停药
to stop medication
xuèyā
血压
blood pressure
dǎngùchún
胆固醇
cholesterol
jiǎnzhòng
减重
weight loss
zhìliáo
治疗
treatment
wéichí
维持
to maintain
yīliáo tuánduì
医疗团队
medical team

News in English

Lifestyle & Culture

Study Finds Weight Regain After Stopping GLP-1 Drugs Is Four Times Faster Than Dieting

Multiple studies published in January 2026 found that patients who stop taking GLP-1 drugs such as Ozempic tend to regain weight rapidly. Compared to people who rely only on diet and exercise, those who stop the drugs regain weight about four times faster.

Multiple medical studies published in January 2026 show that after discontinuing GLP-1 class weight-loss drugs, patients' body weight often rapidly rebounds. Research data indicates that patients taking Ozempic and similar drugs lose an average of approximately 15 kilograms, but stopping medication about one year later typically results in regaining approximately 10 kilograms.

Compared to people relying solely on diet and exercise for weight loss, the weight rebound rate after stopping medication is approximately four times faster. University of Oxford research team pointed out that approximately 17 months after stopping medication, patients' blood pressure and cholesterol levels also return to pre-medication states.

However, a real-world study from Cleveland Clinic covering nearly 8,000 patients shows that many people will restart medication after stopping, with actual rebound situations possibly relatively mild. Multiple experts stated that GLP-1 class drugs are more suitable as long-term maintenance treatment approaches rather than short-term intervention measures.

Currently, the annual cost of Ozempic and similar drugs reaches thousands of dollars, creating relatively heavy financial burdens for long-term use for many patients. Doctors recommend patients communicate fully with medical teams before stopping medication and jointly formulate personalized long-term weight management plans.

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永久冻土
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jiāsù
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to melt / to thaw
rónghuà
融化
ancient / age-old
gǔlǎo
古老
organic carbon
yǒujī tàn
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jīnrì
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chū tǔ
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the Warring States period
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bronze
qīng tóng
青铜
wine vessel
jiǔ qì
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containing inside
nèi cáng
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jù jīn
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approximately
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2300 nián
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(modifier particle)
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