studyyánjiū研究foundfāxiàn发现,to stop usingtíng yòng停用GLP-1 (drug class)GLP-1GLP-1weight lossjiǎnféi减肥drugyào药afterhòu后,most / the majority ofdàduōshù大多数patientshuànzhě患者body weighttǐzhòng体重did notméiyǒu没有significantlydàfú大幅reboundfǎntán反弹。
study
yánjiū
研究
found
fāxiàn
发现
to stop using
tíng yòng
停用
GLP-1 (drug class)
GLP-1
GLP-1
weight loss
jiǎnféi
减肥
drug
yào
药
after
hòu
后
most / the majority of
dàduōshù
大多数
patients
huànzhě
患者
body weight
tǐzhòng
体重
did not
méiyǒu
没有
significantly
dàfú
大幅
rebound
fǎntán
反弹
targeting / regarding
zhēnduì
针对
nearly
jìn
近
8,000 people
bā qiān míng
8000名
patients
huànzhě
患者
possessive particle
de
的
study
yánjiū
研究
found
fāxiàn
发现
to stop using
tíng yòng
停用
GLP-1
GLP-1
GLP-1
type
lèi
类
weight loss
jiǎnféi
减肥
drugs
yàowù
药物
after
hòu
后
most
dàduōshù
大多数
people
rén
人
are able to
nénggòu
能够
through
tōngguò
通过
switching medications
huàn yào
换药
or
huò
或
to change
gǎibiàn
改变
lifestyle
shēnghuó fāngshì
生活方式
to maintain
wéichí
维持
body weight
tǐzhòng
体重
study
yánjiū
研究
shows
xiǎnshì
显示
stopping medication
tíng yào
停药
before
qián
前
patients
huànzhě
患者
on average
píngjūn
平均
lost weight
jiǎnzhòng
减重
8.4 percent
bǎifēnzhī bā diǎn sì
8.4%
stopping medication
tíng yào
停药
one year
yī nián
一年
after
hòu
后
on average
píngjūn
平均
only
jǐn
仅
rose back
huíshēng
回升
0.5 percent
bǎifēnzhī líng diǎn wǔ
0.5%
March 19, 2026 at 4:00 PM
one
yī
一
item (measure word for studies)
xiàng
项
new
xīn
新
study
yánjiū
研究
on / regarding
duì
对
nearly
jìn
近
8,000 people
bā qiān míng
8000名
to stop using
tíng yòng
停用
GLP-1 (weight loss drug class)
GLP-1
GLP-1
type
lèi
类
weight loss
jiǎnféi
减肥
medications
yàowù
药物
possessive particle
de
的
patients
huànzhě
患者
to conduct
jìnxíng
进行
completion particle
le
了
tracking follow-up
zhuīzōng
追踪
analysis
fēnxī
分析
GLP-1
GLP-1
GLP-1
type
lèi
类
drugs
yàowù
药物
include
bāokuò
包括
widely known
guǎng wéi rén zhī
广为人知
possessive particle
de
的
semaglutide (active ingredient)
Sīměigélǔtài
司美格鲁肽
namely
jí
即
Ozempic (brand name)
Àozémǔpǐkè
奥泽姆匹克
and
hé
和
Wegovy (brand name)
Wéigéwéi
维格维
study
yánjiū
研究
found
fāxiàn
发现
stopping the medication
tíng yào
停药
after
hòu
后
body weight
tǐzhòng
体重
significantly
dàfú
大幅
rebounding
fǎntán
反弹
possessive particle
de
的
situation
qíngkuàng
情况
not actually
bìng bù
并不
like
xiàng
像
in the past
yǐwǎng
以往
clinical trials
línchuáng shìyàn
临床试验
showed
xiǎnshì
显示
possessive particle
de
的
that way
nàyàng
那样
common / widespread
pǔbiàn
普遍
patients
huànzhě
患者
at
zài
在
stopping medication
tíng yào
停药
before
qián
前
on average
píngjūn
平均
lost weight by
jiǎnzhòng
减重
approximately
yuē
约
8.4 percent
bǎifēnzhī bā diǎn sì
8.4%
stopping medication
tíng yào
停药
one year
yī nián
一年
after
hòu
后
on average
píngjūn
平均
only
jǐn
仅
rose back by
huíshēng
回升
0.5 percent
bǎifēnzhī líng diǎn wǔ
0.5%
among
zài
在
those who stopped medication
tíng yào
停药
patients
huànzhě
患者
among
zhōng
中
27 percent
bǎifēnzhī èrshíqī
27%
within
zài
在
within one year
yī nián nèi
一年内
switched to
huànyòng
换用
completion particle
le
了
other
qítā
其他
medications
yàowù
药物
20 percent
bǎifēnzhī èrshí
20%
again
chóngxīn
重新
began
kāishǐ
开始
to use
shǐyòng
使用
original
yuánlái
原来
possessive particle
de
的
medication
yàowù
药物
additionally
hái yǒu
还有
14 percent
bǎifēnzhī shísì
14%
possessive particle
de
的
patients
huànzhě
患者
chose
xuǎnzé
选择
through
tōngguò
通过
diet
yǐnshí
饮食
adjustment
tiáozhěng
调整
and
hé
和
exercise
yùndòng
运动
to (purpose marker)
lái
来
to maintain
wéichí
维持
body weight
tǐzhòng
体重
researchers
yánjiū rényuán
研究人员
to point out
zhǐchū
指出
real-world
zhēnshí
真实
world
shìjiè
世界
in
zhōng
中
patients
huànzhě
患者
have
yǒu
有
more
gèng duō
更多
flexible
línghuó
灵活
possessive particle
de
的
treatment
zhìliáo
治疗
options
xuǎnzé
选择
compared with
yǔ
与
clinical trials
línchuáng shìyàn
临床试验
conditions
tiáojiàn
条件
different
bùtóng
不同
stopping medication
tíng yào
停药
possessive particle
de
的
most
zuì
最
common
chángjiàn
常见
reason
yuányīn
原因
is
shì
是
cost / fees
fèiyòng
费用
and
hé
和
insurance
bǎoxiǎn
保险
issues
wèntí
问题
followed by / secondly
qícì
其次
is
shì
是
side effects
fùzuòyòng
副作用
and
hé
和
medication
yàowù
药物
shortage
duǎnquē
短缺
News in English
Lifestyle & CultureLarge Study Finds Most Patients Who Stop GLP-1 Weight Loss Drugs Do Not Experience Dramatic Rebound
A large real-world study of nearly 8,000 patients found that most people who stop GLP-1 weight loss drugs do not experience a dramatic weight rebound. The study showed patients lost an average of 8.4 percent before stopping and regained only 0.5 percent on average after one year.
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