research / studyyánjiū研究to show / to revealxiǎnshì显示，single / one-timedān cì单次gene therapyjīyīn zhìliáo基因治疗injectionzhùshè注射can / is able tokě可to make / to enableshǐ使congenital / hereditaryxiāntiānxìng先天性deafnessěrlóng耳聋patientshuànzhě患者to recover / to restorehuīfù恢复hearingtīnglì听力。
research / study
yánjiū
研究
to show / to reveal
xiǎnshì
显示
single / one-time
dān cì
单次
gene therapy
jīyīn zhìliáo
基因治疗
injection
zhùshè
注射
can / is able to
kě
可
to make / to enable
shǐ
使
congenital / hereditary
xiāntiānxìng
先天性
deafness
ěrlóng
耳聋
patients
huànzhě
患者
to recover / to restore
huīfù
恢复
hearing
tīnglì
听力
Karolinska (Swedish medical university)
Kǎluólínsīkǎ
卡罗林斯卡
medical school
yīxuéyuàn
医学院
and / with
yǔ
与
China
Zhōngguó
中国
cooperative
hézuò
合作
team
tuánduì
团队
(particle)
de
的
latest
zuìxīn
最新
research
yánjiū
研究
to show / to indicate
biǎomíng
表明
a type of
yī zhǒng
一种
new
xīnxíng
新型
gene therapy approach
jīyīn liáofǎ
基因疗法
is capable of
nénggòu
能够
effectively
yǒuxiào
有效
to restore
huīfù
恢复
congenital
xiāntiānxìng
先天性
deafness
ěrlóng
耳聋
patients
huànzhě
患者
(particle)
de
的
hearing
tīnglì
听力
ten (people)
shí míng
十名
to receive
jiēshòu
接受
treatment
zhìliáo
治疗
(particle)
de
的
patients
huànzhě
患者
all / each
jūn
均
within
zài
在
within six months
liù gè yuè nèi
六个月内
to show
xiǎnshì
显示
(directional particle)
chū
出
clear / obvious
míngxiǎn
明显
improvement
gǎishàn
改善
April 3, 2026 at 12:00 PM
according to
jù
据
April 3rd
sì yuè sān rì
四月三日
to release / to publish
fābù
发布
(particle)
de
的
research
yánjiū
研究
report
bàogào
报告
Sweden
Ruìdiǎn
瑞典
Karolinska
Kǎluólínsīkǎ
卡罗林斯卡
medical school
yīxuéyuàn
医学院
and / with
yǔ
与
China
Zhōngguó
中国
research institutions
yánjiū jīgòu
研究机构
jointly
gòngtóng
共同
to carry out
kāizhǎn
开展
(completion particle)
le
了
a
yī xiàng
一项
gene therapy
jīyīn zhìliáo
基因治疗
clinical trial
línchuáng shìyàn
临床试验
researchers
yánjiū rényuán
研究人员
through / by means of
tōngguò
通过
to / toward
xiàng
向
patients
huànzhě
患者
inner ear
nèi ěr
内耳
to inject
zhùshè
注射
synthetic
héchéng
合成
adeno-associated virus (AAV)
xiàn xiānguān bìngdú
腺相关病毒
to deliver
jiāng
将
normal / functioning
zhèngcháng
正常
(particle)
de
的
OTOF (otoferlin gene associated with deafness)
OTOF
OTOF
gene
jīyīn
基因
to deliver to
sòng dá
送达
cochlea (inner ear structure)
ěr wō
耳蜗
to participate in
cānyù
参与
clinical trial
línchuáng shìyàn
临床试验
(particle)
de
的
ten (people)
shí míng
十名
congenital
xiāntiānxìng
先天性
deafness
ěrlóng
耳聋
patients
huànzhě
患者
all
quánbù
全部
to
duì
对
treatment
zhìliáo
治疗
to show / to produce
chǎnshēng
产生
(completion particle)
le
了
positive
jījí
积极
response
fǎnyìng
反应
most / the majority of
duōshù
多数
patients
huànzhě
患者
within
zài
在
to receive
jiēshòu
接受
injection
zhùshè
注射
after
hòu
后
within one month
yī gè yuè nèi
一个月内
then / already
biàn
便
to begin
kāishǐ
开始
to appear
chūxiàn
出现
hearing
tīnglì
听力
improvement
gǎishàn
改善
(particle)
de
的
signs
jìxiàng
迹象
among them
qízhōng
其中
one
yī míng
一名
seven-year-old
qī suì
七岁
girl
nühái
女孩
after
zài
在
treatment
zhìliáo
治疗
four months later
sì gè yuè hòu
四个月后
already
yǐ
已
able to
néng
能
to recover
huīfù
恢复
normal
zhèngcháng
正常
(particle)
de
的
everyday
rìcháng
日常
conversation
duìhuà
对话
ability
nénglì
能力
data
shùjù
数据
to show
xiǎnshì
显示
to receive
jiēshòu
接受
treatment
zhìliáo
治疗
(particle)
de
的
patients
huànzhě
患者
average
píngjūn
平均
sound
shēngyīn
声音
perception
gǎnzhī
感知
threshold
yùzhí
阈值
from
cóng
从
106 decibels
yībǎi líng liù fēnbèi
一百零六分贝
to drop / to decrease
xiàjiàng
下降
to
zhì
至
52 decibels
wǔshíèr fēnbèi
五十二分贝
researchers
yánjiū rényuán
研究人员
to state
biǎoshì
表示
the next phase
xià yī jiēduàn
下一阶段
will
jiāng
将
(object marker)
bǎ
把
this treatment approach
gāi liáofǎ
该疗法
to expand
kuòzhǎn
扩展
to
zhì
至
GJB2 (deafness-related gene)
GJB2
GJB2
and
hé
和
TMC1 (deafness-related gene)
TMC1
TMC1
and other
děng
等
other
qítā
其他
common
chángjiàn
常见
deafness-causing
zhì lóng
致聋
gene
jīyīn
基因
(particle)
de
的
patients
huànzhě
患者
this
cǐ cì
此次
research
yánjiū
研究
result / findings
jiéguǒ
结果
is considered to be
bèi rènwéi
被认为
is
shì
是
hereditary / genetic
yíchuánxìng
遗传性
deafness
ěrlóng
耳聋
treatment
zhìliáo
治疗
field / domain
lǐngyù
领域
(particle)
de
的
major / significant
zhòngdà
重大
breakthrough
tūpò
突破
is expected to
yǒuwàng
有望
within
zài
在
future
wèilái
未来
within the coming years
shù nián nèi
数年内
to benefit
zàofú
造福
global
quánqiú
全球
millions of
shù bǎi wàn
数百万
deaf
ěrlóng
耳聋
patients
huànzhě
患者
News in English
Lifestyle & CultureSingle Gene Therapy Injection Restores Hearing in Children Born Deaf, Study Finds
New research by Karolinska medical school and Chinese partner institutions shows a gene therapy injection can effectively restore hearing in people with congenital deafness. All ten patients in the trial showed improvement within six months.
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