Nature Medicine journalZìrán Yīxué《自然医学》studyyánjiū研究:fasting-mimickingfǎng jìn shí仿禁食dietyǐnshí饮食cankě可significantlyxiǎnzhù显著relievehuǎnjiě缓解Crohn diseaseKèluóēn bìng克罗恩病symptomszhèngzhuàng症状。
Nature Medicine journal
Zìrán Yīxué
《自然医学》
study
yánjiū
研究
fasting-mimicking
fǎng jìn shí
仿禁食
diet
yǐnshí
饮食
can
kě
可
significantly
xiǎnzhù
显著
relieve
huǎnjiě
缓解
Crohn disease
Kèluóēn bìng
克罗恩病
symptoms
zhèngzhuàng
症状
a
yī xiàng
一项
published
fābiǎo
发表
in
yú
于
Nature Medicine
Zìrán Yīxué
《自然医学》
structural particle
de
的
randomized
suíjī
随机
controlled
duìzhào
对照
clinical
línchuáng
临床
trial
shìyàn
试验
reveals
jiēshì
揭示
each month
měi yuè
每月
for five consecutive days
liánxù wǔ tiān
连续五天
following
zūnxún
遵循
fasting-mimicking
fǎng jìn shí
仿禁食
diet
yǐnshí
饮食
structural particle
de
的
Crohn disease
Kèluóēn bìng
克罗恩病
patients
huànzhě
患者
among
zhōng
中
approximately 69 percent
yuē 69%
约69%
achieved
dádào
达到
clinical
línchuáng
临床
remission
huǎnjiě
缓解
criteria
biāozhǔn
标准
significantly
xiǎnzhù
显著
higher than
gāoyú
高于
control group
duìzhào zǔ
对照组
44 percent
de 44%
的44%
April 3, 2026 at 10:00 AM
a
yī xiàng
一项
published
fābiǎo
发表
in
yú
于
Nature Medicine
Zìrán Yīxué
《自然医学》
journal
zázhì
杂志
structural particle
de
的
randomized
suíjī
随机
controlled
duìzhào
对照
clinical
línchuáng
临床
trial
shìyàn
试验
reveals
jiēshì
揭示
fasting-mimicking
fǎng jìn shí
仿禁食
diet
yǐnshí
饮食
for
duì
对
mild-to-moderate
qīng zhōng dù
轻中度
Crohn disease
Kèluóēn bìng
克罗恩病
patients
huànzhě
患者
structural particle
de
的
therapeutic efficacy
liáoxiào
疗效
has
jùyǒu
具有
statistical
tǒngjìxué
统计学
significance
yìyì
意义
Stanford University
Sītǎnfú Dàxué
斯坦福大学
research team
yánjiū tuánduì
研究团队
enrolled
zhāomù
招募
97
jiǔshíqī míng
97名
patients
huànzhě
患者
randomly
suíjī
随机
divided into
fēnwéi
分为
fasting-mimicking
fǎng jìn shí
仿禁食
diet group
yǐnshí zǔ
饮食组
and
yǔ
与
control group
duìzhào zǔ
对照组
follow-up
suífǎng
随访
period
zhōuqī
周期
was
wéi
为
three months
sān gè yuè
三个月
diet group
yǐnshí zǔ
饮食组
patients
huànzhě
患者
each month
měi yuè
每月
for consecutive
liánxù
连续
five days
wǔ tiān
五天
jiāng
将
caloric
rèliàng
热量
intake
shèrù
摄入
restricted
xiànzhì
限制
to
zài
在
700 to 1,100 calories
700 zhì 1100 kǎlùlǐ
700至1100卡路里
zhījiān
之间
with
yǐ
以
plant-based
zhíwùxìng
植物性
foods
shíwù
食物
as the primary source
wéi zhǔ
为主
results
jiéguǒ
结果
showed
xiǎnshì
显示
diet group
yǐnshí zǔ
饮食组
69.2 percent
69.2%
69.2%
of
de
的
patients
huànzhě
患者
achieved
dádào
达到
completion marker
le
了
primary
zhǔyào
主要
clinical
línchuáng
临床
endpoint
zhōngdiǎn
终点
whereas
ér
而
control group
duìzhào zǔ
对照组
this
zhè yī
这一
proportion
bǐlì
比例
was only
jǐn wéi
仅为
43.8 percent
43.8%
43.8%
the study
yánjiū
研究
also
hái
还
found
fāxiàn
发现
diet group
yǐnshí zǔ
饮食组
fecal
fèn biàn
粪便
calprotectin
gài wèi dànbái
钙卫蛋白
levels
shuǐpíng
水平
significantly
xiǎnzhù
显著
declined
xiàjiàng
下降
indicating
biǎomíng
表明
intestinal
chángdào
肠道
inflammation
yánzhèng
炎症
was
dédào
得到
completion marker
le
了
effectively
yǒuxiào
有效
controlled
kòngzhì
控制
researchers
yánjiū rényuán
研究人员
noted
zhǐchū
指出
fasting-mimicking
fǎng jìn shí
仿禁食
diet
yǐnshí
饮食
structural particle
de
的
mechanism of action
zuòyòng jīzhì
作用机制
may
kěnéng
可能
involve
shèjí
涉及
on
duì
对
gut
chángdào
肠道
microbiome
wēi shēngtài
微生态
and
jí
及
immune
miǎnyì
免疫
regulatory
tiáojié
调节
pathways
tōnglù
通路
structural particle
de
的
multiple
duōchóng
多重
interventions
gānyù
干预
given that
jiànyú
鉴于
some
bùfèn
部分
Crohn disease
Kèluóēn bìng
克罗恩病
patients
huànzhě
患者
to
duì
对
existing
xiànyǒu
现有
medications
yàowù
药物
treatment
zhìliáo
治疗
response
fǎnyìng
反应
poor
bùjiā
不佳
or
huò
或
have
cúnzài
存在
side effect
fù zuòyòng
副作用
concerns
gùlǜ
顾虑
this
gāi
该
dietary
yǐnshí
饮食
intervention
gānyù
干预
regimen
fāng an
方案
holds
jùyǒu
具有
important
zhòngyào
重要
clinical
línchuáng
临床
reference value
cānkǎo jiàzhí
参考价值
academic community
xuéjiè
学界
called for
hūyù
呼吁
conducting
kāizhǎn
开展
larger-scale
guīmó gèng dà
规模更大
follow-up
suífǎng
随访
period
shíjiān
时间
longer
gèng cháng
更长
structural particle
de
的
follow-up
hòuxù
后续
studies
yánjiū
研究
in order to further
yǐ jìnyībù
以进一步
evaluate
pínggū
评估
this
gāi
该
dietary
yǐnshí
饮食
therapy
liáofǎ
疗法
structural particle
de
的
long-term
cháng qī
长期
safety
ānquánxìng
安全性
and
yǔ
与
efficacy
yǒuxiào xìng
有效性
News in English
Lifestyle & CultureNature Medicine Study Finds Fasting-Mimicking Diet Significantly Eases Crohn Disease Symptoms
A randomized controlled trial published in Nature Medicine found that a five-day-per-month fasting-mimicking diet led 69 percent of Crohn disease patients to achieve clinical response, compared with 44 percent in the control group.
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